USP Kinase Inhibitors Afatinib 439081-18-2 Gilotrif for Lung Cancer
1. Quick Details:
2. What is Afatinib ?
|Product name:||Afatinib (BIBW 2992);Gilotrif|
BIBW 2992;BIBW2992 Afatinib;Afatinib (BIBW
|Appearance:||White or Nearly White Crystalline Powder|
|Deliver time:||About 5 days|
|Deliver methods:||TNT,EMS,HKEMS,DHL,ect.(door to door)|
Afatinib is pronounced aff-a-tin-ib. It has the brand name Giotrif
(jee-oh-triff). It is a type of biological therapy called a
tyrosine kinase inhibitor (TKI). It is a treatment for non small
cell lung cancer that has spread outside the lung or to other parts
of the body.
It has received regulatory approval for use as a treatment for
non-small cell lung cancer,although there is emerging evidence to
support its use in other cancers such as breast cancer.
3. How afatinib works:
This type of drug works by blocking particular proteins on cancer
cells that encourage the cancer to grow. Afatinib blocks proteins
called epidermal growth factor receptors (EGFR). Cancers that have
these receptors are called EGFR positive.
Between 10 and 15 people out of every 100 with non small cell lung
cancer (10 to 15%) have EGFR positive cancer. Doctors check your
cancer cells to see if they have the receptors before you have this
Afatinib may shrink the cancer or stop it growing for a time
4. Uses and fuction:
Afatinib is used to treat a certain type of lung cancer (non-small
cell lung cancer) that has spread to other parts of the body. It
belongs to a class of drugs known as kinase inhibitors. It works by
slowing or stopping the growth of cancer cells. It binds to a
certain protein (epidermal growth factor receptor-EGFR) in some
5. Mechanism of action:
Like lapatinib and neratinib, afatinib is a protein kinase
inhibitor that also irreversibly inhibits human epidermal growth
factor receptor 2 (Her2) and epidermal growth factor receptor
(EGFR) kinases. Afatinib is not only active against EGFR mutations
targeted by first generation tyrosine-kinase inhibitors (TKIs)
likeerlotinib or gefitinib, but also against mutations such as
T790M which are not sensitive to these standard therapies.Because
of its additional activity against Her2, it is being investigated
for breast cancer as well as other EGFR and Her2 driven cancers.
|Description||Off-white powder||Off-white powder|
|Residue on Ignition||≤0.10%||0.05%|
|Loss on Drying||≤0.50%||0.15%|
|Conclusion||It complies with EnterpriseStandard|
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|ACE 031||1 mg/vial, 10 vials/kit|
|Follistatin 315||1 mg/vial, 10 vials/kit|
|Follistatin 344||1 mg/vial, 10 vials/kit|
|MGF||2 mg/vial, 10 vials/kit|
|PEG - MGF||2 mg/vial, 10 vials/kit|
|DSIP||2 mg/vial, 10 vials/kit|
|TB500||2 mg/vial, 10 vials/kit|
|Oxytocin||2 mg/vial, 10 vials/kit|
|Hexarelin||2 mg/vial, 10 vials/kit|
|Triptorelin||2 mg/vial, 10 vials/kit|
|Ipamorelin||2 mg/vial, 10 vials/kit|
|Sermorelin||2 mg/vial, 10 vials/kit|
|Gonadorelin||2 mg/vial, 10 vials/kit|
|Tesamorelin||2 mg/vial, 10 vials/kit|
|BPC 157||2 mg/vial, 10 vials/kit|
|AOD-9604||2 mg/vial, 10 vials/kit|
|H 176-191||2 mg/vial, 10 vials/kit|
|CJC-1295||2 mg/vial, 10 vials/kit|
|CJC-1295 DAC||2 mg/vial, 10 vials/kit|
|GHRP-2||5 mg/vial, 10 vials/kit|
|GHRP-6||5 mg/vial, 10 vials/kit|
|Selank||5 mg/vial, 10 vials/kit|
|GHRP-2||10 mg/vial, 10 vials/kit|
|GHRP-6||10 mg/vial, 10 vials/kit|
|Epitalon||10 mg/vial, 10 vials/kit|
|PT-141||10 mg/vial, 10 vials/kit|
|Gonadorelin||10 mg/vial, 10 vials/kit|
|Melanotan II||10 mg/vial, 10 vials/kit|
Hubei Shinrezing Pharmaceutical Technology Co.,Ltd.(hereafter
shorted as Shinrezing) is located in Wuhan Donghu High-Tech
Economic Development Zone and established in 2008 with registered
capital is RMB 10 million yuan (about USD 1.5 million ). Its
manufacturing base is located in Dawu Industrial Park in Dawu
County, Xiaogan City, Hubei Province which is built in 2010 with
25,000 square meters covered area.
Shinrezing is a rapid growing enterprise, which integrates the
production, R&D, sales and trading of APIs, steroid raw
materials, pharmaceutical intermediates, plant extracts, other
kinds of organic intermediates etc. Shinrezing is not only a
manufacturing company but also a trade company, it also has very
good cooperation relationships with some manufacturers qualified
with GMP, DMF to meet the different customers' needs from grams to
tonnage quantity, which makes Shinrezing to be more flexible and
easily to supply highly cost-effective products with high quality
and better service to customers.
Shinrezing always stands in high starting, high stand and high
quality, and masters strict management for production procedure and
quality control. All the products must pass our quality test before
being sending to customers. Shinrezing's products have been
exported to more than 50 countries and regions all over the world,
including United States, Europe, Japan, Korea, Russia, Hong kong,
Taiwan and so on, and enjoy a good reputation from domestic and
Shinrezing's mission is: "Innovative and Pragmatic, Mutual
Benefits, Serve the World". Every staff member will keep this in
mind all the time, and enforce it at every detail of operation and
management of the company. We are always trying our best to offer
the best services and the most competitive prices with high quality
goods for our customers. All honors belong to the past, Shinrezing
people will do their best to develop and produce more perfect
product and contribute to the chemical pharmaceutical industries
We are confident that Shinrezing will be your best solution.
Q1: Have your Product Quality been Approved by Third Party Lab?
A: Yes, All products are strictly tested by our QC, confirmed by QA
and approved by third party lab in China, USA, Canada, Germany, UK,
Italy, France etc. So you will be assured with Good Quality if you
Q2:How do you treat quality complaint?
A:First of all, our QC department will do strict examination of our
export products by HPLC, UV, GC ,
TLC and so on in order to reduce the quality problem to near zero.
If there is a real quality problem ,caused by us, we will send you
free goods for replacement or refund your loss.
Q3: Do you Accept Sample Order?
A: Yes, we accept small order from 10g, 100g and 1kg for your
evaluation quality of our goods.
Q4: Is there any discount?
A: Yes, for larger quantity, we always support with better price.
Q5:Do you accept VISA business credit card ?
A:Sorry we don't accept VISA credit card,
we'd like to accept bank transfer, Western Union or Paypal or
Q6:How long does it take to the goods arrived ?
It is Depending on your location,
For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.
For mass order, please allow 5-8 days by Air, 20-35 days by Sea.
Q7 Do you have any reshipment policy ?
we have good after-sale service and re-shipment policy if the
Our long association with our clients has brought great benefits
We always take the upmost care in the packaging of our products
our clients will confirm this as even they struggle to find them
without help at times.
But in spite of our best efforts it is still possible will seize a
small number of packages.
In this circumstance we promise reship free to establish long term
Q8 :Can I get a sample?
A: Of course. For most products we can provide you a free sample,
while the shipping cost shouldundertake by your side.
We have formed a technology and management team that cooperate
closely with some overseas Labs all speak highly of our safe
shipping and goods .
please donot hesitate to contact us.