L - Arginine Amino Acid Powder for Erectile dysfunction and High
blood pressure CAS 74-79-3
Arginine ( abbreviated as Arg or R ) encoded by the codons CGU,
CGC, CGA, CGG, AGA, and AGG is an α-amino acid that is used in the
biosynthesis of proteins.
Arginine is classified as a semiessential or conditionally
essential amino acid, depending on the developmental stage and
health status of the individual. Preterm infants are unable to
synthesize or create arginine internally, making the amino acid
nutritionally essential for them. Most healthy people do not need
to supplement with arginine because it is a component of all
protein-containing foods and their body produces sufficient
Arginine was first isolated from a lupin seedling extract in 1886
by the German chemist Ernst Schultze. It contains an α-amino group
( which is in the protonated −NH3+ form under biological conditions
), an α-carboxylic acid group ( which is in the deprotonated −COO−
form under biological conditions ), and a side chain of a 3-carbon
aliphatic straight chain capped by a complex guanidinium,
classifying it as a charged ( at physiological pH ), aliphatic
Arginine plays an important role in cell division, the healing of
wounds, removing ammonia from the body, immune function, and the
release of hormones.
The roles of endogenous arginine include:
Precursor for the synthesis of nitric oxide.
Healing of injuries, possibly through mTOR protein kinase.
Regulate blood pressure.
The distributing basics of the moderate structure found in
geometry, charge distribution, and ability to form multiple H-bonds
make arginine ideal for binding negatively charged groups. For this
reason, arginine prefers to be on the outside of the proteins,
where it can interact with the polar environment.
Incorporated in proteins, arginine can also be converted to
citrulline by PAD enzymes. In addition, arginine can be methylated
by protein methyltransferases.
Arginine is the immediate precursor of nitric oxide ( NO ), urea,
ornithine, and agmatine; is necessary for the synthesis of
creatine; and can also be used for the synthesis of polyamines (
mainly through ornithine and to a lesser degree through agmatine ),
citrulline, and glutamate. As a precursor of nitric oxide, arginine
may have a role in the treatment of some conditions where
vasodilation is required. The presence of asymmetric
dimethylarginine ( ADMA ), a close relative, inhibits the nitric
oxide reaction; therefore, ADMA is considered a marker for vascular
disease, just as L-arginine is considered a sign of a healthy
L-arginine is generally recognized as safe ( GRAS-status ) at
intakes of up to 20 grams per day.
|Item||Specifications (USP)||Specifications (AJI)|
|Description||White crystals or crystalline powder||White crystals or crystalline powder|
|Identification||Infrared absorption spectrum||Infrared absorption spectrum|
|Specific rotation||+26.3 °- +27.7°||+26.9 °- +27.9°|
|State of solution||---||≥ 98.0%|
|Chloride (Cl)||≤ 0.05%||≤ 0.020%|
|Ammonium (NH4)||---||≤ 0.02%|
|Sulfate (SO4)||≤ 0.03%||≤ 0.020%|
|Iron (Fe)||≤ 0.003%||≤ 10PPm|
|Heavy metals (Pb)||≤ 0.0015%||≤ 10PPm|
|Arsenic (As2O3)||---||≤ 1PPm|
|Other amino acids||---||Chromatographically not detectable|
|Loss on drying||≤ 0.5%||≤ 0.5%|
|Residue on ignition||≤ 0.3%||≤ 0.10%|
|Organic volatile impurities||Meets the requirements||---|