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59122-46-2 misoprostol excellent products for gastric and duodenal ulcers, hemorrhagic gastritis

Categories Steroid
Brand Name: South arrow
Model Number: 21409-26-7
Certification: SGS
Place of Origin: China
MOQ: 10g
Price: Please contact
Payment Terms: T/T, Western Union, MoneyGram
Packaging Details: 1kg/aluminium foil bag or as required
Supply Ability: Regular stock
CAS: 21409-26-7
MF: C19H24N2
MW: 280.40726
Purity: 99.5%
Appearance: Light yellow powder
Use: Fentanyl
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    59122-46-2 misoprostol excellent products for gastric and duodenal ulcers, hemorrhagic gastritis

    Product Name: Misoprostol
    Synonyms: CYTOTEC;9-OXO-11ALPHA,16-DIHYDROXY-16-METHYL-PROST-13E-EN-1-OIC ACID;9-OXO-11ALPHA,16-DIHYDROXY-16-METHYL-PROST-13E-EN-1-OIC ACID, METHYL ESTER;(11A,13E)-(-)-11,16-DIHYDROXY-16-METHYL-9-OXO-PROST-13-EN-1-OIC ACID METHYL ESTER;(11alpha,13e)-(+)-11alpha,16-dihydroxy-16-methyl-9-oxoprost-13e-en-1-oic acid methyl ester;(+/-)-15-DEOXY-[16RS]-16-HYDROXY-16-METHYLPROSTAGLANDIN E1;(+/-)-15-DEOXY-(16R,S)-16-HYDROXY-16-METHYL-PROSTAGLANDIN E1, METHYL ESTER;SC-29333
    CAS: 59122-46-2
    MF: C22H38O5
    MW: 382.54
    Product Categories: Active Pharmaceutical Ingredients;Prostaglandins;Prostaglandin;Fatty Acid Derivatives & Lipids;Glycerols;Intermediates & Fine Chemicals;Pharmaceuticals;Prostanoid receptor and related;API;Inhibitors

    mp 261-263°C
    storage temp. −20°C
    CAS DataBase Reference 59122-46-2(CAS DataBase Reference)
    EPA Substance Registry System Prost-13-en-1-oic acid, 11,16-dihydroxy-16-methyl- 9-oxo-, methyl ester, (11.alpha.,13E)-(59122-46-2)

    Chemical Properties White Solid
    Usage antiulcerative;prostaglandin E1 analog that inhibits gastric acid secretion
    Usage A cytoprotective prostaglandin PGE1 analogue
    Biological Activity Cytoprotective prostaglandin E 1 analog that displays agonist activity at EP receptors. K i values are 120, 250, 67 and 67 nM at cloned mouse EP 1 , EP 2 , EP 3 and EP 4 receptors respectively. Prevents NSAID-induced gastric ulceration.

    [identification] (1) take the product of about 1 mg, and ethanol was dissolved with 5ml, shake, 0.5ml, plus 1% of m-dinitrobenzene ethanol solution 1.5ml, set in ice bath cooling, avoid light plus 10% potassium hydroxide B drunk solution 1.5ml, the solution is shown in pink. (2) the infrared absorption spectrum of the product should be consistent with the atlas of the reference (Chinese Pharmacopoeia 2000 edition of the two Annex IV C). Donor [check] about material taken this product with acetonitrile water (55:45) were made per ml containing 1 ml of sample solution and / Mg containing 50 g of the pre trial solution, according to the content determination under the chromatographic conditions, prefetching test solution 20 UL injection liquid chromatograph, adjust the detection sensitivity, the principal component chromatographic peak peak height is about records recorded in full range of 20% ~ 25%, and the amount of sample solution 20 UL sample, record the chromatograms to the main component peaks retention time of 3 times by peak area normalization method to calculate all impurity peak area and the total peak area ratio of not more than 3.5%, the biggest impurity peak area of not more than 2.5%. [content] by high performance liquid chromatography (China Pharmacopoeia 2000 two appendix V D) determination. Chromatographic conditions and system suitability test with octadecylsilane bonded silica as filler, acetonitrile water (55:45) as the mobile phase, detection wavelength 200nm and theoretical plate number according to the peak of misoprostol calculation should not be less than 2000. Determination method and take proper amount of the product, accurately weighed, with mobile phase dissolution and dilution quantitative made per ml containing approximately 0.2 mg solution, precision measuring take 10 mu l into the liquid chromatograph, record the chromatograms; another take misoprostol control products, with the method of determination. According to the external standard method to calculate the peak area, that is, the. [category] termination of early pregnancy. [storage] sealed with nitrogen, preserved in cold storage.

    Mol File:59122-46-2.mol
    Misoprostol Structure
    Quality 59122-46-2 misoprostol excellent products for gastric and duodenal ulcers, hemorrhagic gastritis for sale
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